The 2024 NFL season continues with a intriguing NFL Week 4 schedule that features some very pivotal early-season games.
Among them: The Dallas Cowboys at New York Giants on Thursday Night Football, the New Orleans Saints at Atlanta Falcons, the Minnesota Vikings at Green Bay Packers, the Philadelphia Eagles at Tampa Bay Buccaneers, the Kansas City Chiefs at Los Angeles Chargers, the Buffalo Bills at Baltimore Ravens on Sunday Night Football and the Tennessee Titans at Miami Dolphins and Seattle Seahawks at Detroit Lions on Monday Night Football.
Which teams will win their NFL Week 4 games?
Check out our NFL Week 4 picks and NFL Week 4 predictions for the 16 NFL games this week.
All times MST. Click on each for picks, predictions and NFL Week 4 odds for that matchup.
NFL Week 4 picks: Cowboys vs Giants | Saints vs Falcons | Bengals vs Panthers | Rams vs Bears | Vikings vs Packers | Jaguars vs Texans | Steelers vs Colts | Broncos vs Jets | Eagles vs Buccaneers | Commanders vs Cardinals | Patriots vs 49ers | Chiefs vs Chargers | Browns vs Raiders | Bills vs Ravens | Titans vs Dolphins | Seahawks vs Lions | The Arizona Republic's predictions
NFL Week 4 predictions:ESPN matchup predictor's picks, win probabilities for this week
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Thursday Night Football prediction, Sept. 26
Dallas Cowboys at New York Giants, 5:15 p.m., Prime Video (stream on Amazon)
The Cowboys have allowed 89 points this season. The Giants might be the perfect remedy for their defensive woes as New York has scored just 45 points.
Prediction: Cowboys 24, Giants 20
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Sunday early NFL football game predictions, Sept. 29
New Orleans Saints at Atlanta Falcons, 10 a.m., FOX (stream with free trial from FUBO)
Atlanta can't afford to fall to 0-3 at home to start the season. We don't think Kirk Cousins and the Falcons will win this NFC South clash.
Prediction: Falcons 27, Saints 20
Cincinnati Bengals at Carolina Panthers, 10 a.m., FOX (stream with free trial from FUBO)
The Panthers look like a different team with Andy Dalton at quarterback. We just don't think that team is good enough to beat Cincinnati.
Prediction: Bengals 28, Panthers 21
Los Angeles Rams at Chicago Bears, 10 a.m., FOX (stream with free trial from FUBO)
The Rams might just have turned around their season with that rally against the 49ers.
Prediction: Rams 23, Bears 20
Minnesota Vikings at Green Bay Packers, 10 a.m., CBS (stream with free trial from FUBO)
The Vikings have been the surprise of the NFL so far this season. Can Sam Darnold and company stay atop the NFC North? Yes, with a defense that has only allowed 10 points per game, they can.
Prediction: Vikings 27, Packers 20
Jacksonville Jaguars at Houston Texans, 10 a.m., CBS (stream with free trial from FUBO)
The Texans were humbled by the Vikings in Week 3. C.J. Stroud and company will get back on track against the Jaguars in Week 4.
Prediction: Texans 21, Jaguars 17
Pittsburgh Steelers at Indianapolis Colts, 10 a.m.. CBS (stream with free trial from FUBO)
The Steelers' defense is elite. It has allowed 26 points in three games. There's no reason it shouldn't feast on Anthony Richardson and the Colts.
Prediction: Steelers 20, Colts 14
Denver Broncos at New York Jets, 10 a.m.. CBS (stream with free trial from FUBO)
The Broncos impressed with their win over the Buccaneers. A win over the Jets on the road would really impress. We just don't see it happening with a rookie QB.
Prediction: Jets 27, Broncos 16
Philadelphia Eagles at Tampa Bay Buccaneers, 10 a.m., FOX (stream with free trial from FUBO)
If Denver can rush for 136 yards on Tampa Bay, how many yards can Saquon Barkley and the Eagles gain on the ground against the Buccaneers?
Prediction: Eagles 24, Buccaneers 21
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Washington Commanders at Arizona Cardinals, 1:05 p.m., FOX (stream with free trial from FUBO)
Washington QB Jayden Daniels started his college career at Arizona State. Commanders OC Kliff Kingsbury previously coached the Cardinals. Their homecomings won't go well.
Prediction: Cardinals 31, Commanders 20
New England Patriots at San Francisco 49ers, 1:05 p.m., FOX (stream with free trial from FUBO)
We think the 49ers are too good to fall to 1-3 on the season, even with all their injuries, but this team isn't the same without Christian McCaffrey.
Prediction: 49ers 24, Patriots 13
Kansas City Chiefs at Los Angeles Chargers, 1:25 p.m., CBS (stream with free trial from FUBO)
It hasn't been pretty, but the Chiefs just find ways to win. Patrick Mahomes will find a way to win this game in Los Angeles.
Prediction: Chiefs 20, Chargers 17
Cleveland Browns at Las Vegas Raiders, 1:25 p.m., CBS (stream with free trial from FUBO)
This game could be very low-scoring due to the struggles of both offenses. We trust the home team's offense a little more right now.
Prediction: Raiders 17, Browns 13
NFL Week 4 odds:Point spreads, moneylines, over/unders for betting on games this week
Sunday Night Football prediction, Sept. 29
Buffalo Bills at Baltimore Ravens, 5:20 p.m., NBC (stream with Peacock)
If the Ravens can get to 2-2 after the 0-2 start, it will be a great sign for the rest of their season. We think the defense will be key in beating the Bills.
Prediction: Ravens 24, Bills 20
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Monday Night Football predictions, Sept. 30
Tennessee Titans at Miami Dolphins, 4:30 p.m., ESPN, ESPN Deportes (stream with free trial from FUBO)
The Titans are favored in this game due to Miami's offensive struggles and quarterback situation. Will Levis will do enough in this game to get Tennessee in the win column.
Prediction: Titans 20, Dolphins 16
Seattle Seahawks at Detroit Lions, 5:15 p.m., ABC, ESPN+ (stream with free trial from FUBO)
The Seahawks' surprising 3-0 start has been impressive, but the Lions represent a step up in competition.
Prediction: Lions 27, Seahawks 20
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